Nattokinase NSK-SD™ is a particularly potent medicinal food because it enhances the body's natural ability to fight inadvertent blood clots in several different ways and has many benefits including convenience of oral administration, confirmed efficacy, prolonged effects, cost effectiveness, and can be used preventatively. It is a naturally occurring food, dietary supplement that has demonstrated stability in the gastrointestinal tract. The properties of NSK-SD™ closely resemble those properties of plasmin so it dissolves fibrin directly. NSK-SD™ has specific fibrinolytic activity to cross-linked fibrin 6 times more efficient than by plasmin.

In a pilot study of 20 patients, NSK-SD™ was shown to reduce blood pressure parameters in 80 percent of patients; the ingredient also reduced whole blood viscosity. A larger follow-up study of 80 patients showed similar efficacy in blood pressure parameters and pulse pressure.